A gene that has the potential to cause cancer is known as an oncogene. These genes are frequently altered or overexpressed in tumour cells. When vital functions are disrupted or fail, most normal cells will undergo a predetermined kind of fast cell death (apoptosis). An oncogene is a mutant gene that plays a role in cancer development. Oncogenes are known as proto-oncogenes when they are not altered and have a role in cell division regulation. Some oncogenes function similarly to the accelerator pedal in an automobile, causing a cell to divide. The activation of oncogenes involves genetic changes to cellular proto oncogenes. The consequence of these genetic alterations is to confer a growth advantage to the cell. Three genetic mechanisms activate oncogenes in human neoplasms: (1) mutation, (2) gene amplification, and (3) chromosome rearrangements.

Clinical & Experimental Oncology publishes research that makes a significant contribution an advancing knowledge for cancer diagnosis and therapy. The journal is using online manuscript submission, review and tracking systems of SciTechnol for quality and quick review processing. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process. Publishers can see what manuscripts are in the pipeline awaiting publication. Email is sent automatically to appropriate parties when significant events occur.

Submit manuscripts at https://www.scholarscentral.org/submissions/clinical-experimental-oncology.html or as an E-mail attachment to the editorial office at: submission@scietchnol.com

Best Regards,
Editorial Coordinator
Journal of Clinical & Experimental Oncology
Whatsapp: +44-151-808-0171
E-mail: clinoncol@clinicalmedicaljournal.com